Science Article: Unveiling the Chinese Immune Multi-Omics Atlas (CIMA)
Our recent study in Science provides a comprehensive single-cell multi-omics landscape of the Chinese immune system, ...
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Found 79 posts in this category
Decoding the Rapid Growth of Bamboo via Single-Cell Spatiotemporal Atlas
Our recent study in PNAS leverages Stereo-seq to provide the first high-resolution characterization of intercalary me...
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Nature: A Multilineage Organoid Model of the Human Stomach - Breakthrough: Human Gastroids Model Self-Organized Patterning in Stomach Development
Our recent study published in Nature introduces “Human Gastroids”—multilineage organoids that recapitulate the comple...
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Exploring Antarctic Krill Mitogenomes: Insights into Genetic Diversity and Population Dynamics
Antarctic krill (Euphausia superba), a keystone species in the Southern Ocean ecosystem, plays a pivotal role in glob...
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Tertiary Lymphoid Organ-like Structures in Carotid Artery Plaques: A Breakthrough in Understanding Plaque Instability
Tertiary lymphoid organ-like structures in human atherosclerosis contribute to plaque instability. Xin Liu, on behalf...
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Single‐Cell Multiome Reveals Root Hair‐Specific Responses to Salt Stress in Non‐Heading Chinese Cabbage
Our recent paper introduced findings on mechanisms underlying salt-tolerance in non-heading Chinese cabbage using sin...
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Review Article on Spatial Omics for Plant Research
Our recent review paper comprehensively introduced spatial transcriptome technologies and their applications in plant...
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Soybean Transcriptomic Atlas
We generated Bulk, Single-Cell, and Spatial Transcriptome Data for Soybean to Unveil Mechanisms Underlying its Organ ...
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New Paper Unveils Spatiotemporal Atlas of Mouse Heart Development
We’re thrilled to announce that XinLab has published a new paper in GigaScience (2025, Vol. 14) titled “Exploring the...
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Lamprey Cell Atlas Study Reveals Natterin's Role in Fat Browning
A study co-led by Xin Liu (BGI Research / XinLab), Guangyi Fan (BGI Research), Qingwei Li (Liaoning Normal University...
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Conserved Chloroplast Genomes of Heliconia Revealed
We’re excited to share that XinLab has published a new study in Frontiers in Plant Science (2025, Vol. 15) titled “Un...
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Decoding the Genomic and Cis-Regulatory Basis of Plastic C3-C4 Photosynthesis
Our recent study reveals how Eleocharis baldwinii switches between C3 and C4 photosynthesis through environmentally-t...
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Cell Article: Genomic Insights into the Population Dynamics and Adaptation of Hadal Amphipods
Our recent study in Cell, based on the genomes of over 600 deep-sea amphipods, reveals how host-symbiont interactions...
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Dynamic TE Shaping Plant Evolution and Crop Traits
We analyzed 811 plant genomes across 119 species to create an unprecedented atlas of recent transposable element acti...
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Multi-omics Landscape and Molecular Basis of Radiation Tolerance in a Tardigrade
In our latest collaborative project, we delved deep into the molecular basis of radiation tolerance in a newly identi...
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Massive Genomic Study Catalogues Marine Microbes
🌊 BGI Research Team Unveils Vast Marine Microbial Diversity and Biotechnological Potential in Nature and successfully...
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mtscATAC-seq based on DNBelab C4 published
Our recent paper in Aging Cell described our recently developed single-cell mitochondrial sequencing methods. Here we...
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Mapping Drought Tolerance in Chickpea: Insights from Whole Genome Resequencing of a MAGIC Population
In our ongoing long-term collaboration with Dr. Rajeev Varshney, our team has taken a further step forward in underst...
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Chromosome-Scale Genome of Chitala ornata Illuminates Early Teleost Evolution
Chromosome-Scale Genome of Chitala ornata Illuminates Early Teleost Evolution
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Cicer Super-Pangenome Study Offers Insights for Chickpea Improvement
Published online in Nature Genetics on May 23, 2024, a study presents genomes of eight wild chickpea relatives and a ...
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Rattan Phylogeny based on the Calamus tetradactylus Chloroplast Genome
Our recent study published in BMC Genomic Data by Zhang et al. provides the first complete chloroplast genome sequenc...
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Cellular and Molecular Insights into Fibrosis and Resolution in the Bleomycin-Induced Pulmonary Fibrosis Mouse Model
Pulmonary fibrosis is a chronic lung condition with limited treatment options and significant mortality rates. To bet...
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Genomic Features and Genetic Basis of Tooth Development in Characiformes
Fish, as the most ancient vertebrates, exhibit many unique characteristics compared to later-evolving vertebrates. Ou...
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Chromosome-Level Genome of Butterflyfish Reveals Unique Color Patterns and Morphological Features
Butterflyfishes (family Chaetodontidae) are iconic reef dwellers, renowned for their vibrant color patterns and speci...
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Chromosome-Level Antarctic Krill Genome Unlocks Insights into Adaptations and Population Dynamics
Antarctic krill (Euphausia superba), Earth’s most abundant wild animal, plays a pivotal role in the Southern Ocean ec...
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Symbiont-Screener: Efficient Separation of Host and Symbiont Sequences for Long-Read Metagenomics
The phenomenon of symbiosis is widespread in nature, with biological samples often containing data from multiple spec...
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A Comprehensive Chickpea Genetic Variation Map: Insights from 3,366 Genomes
Chickpea (Cicer arietinum), one of the world’s most important legume crops, has long been a focal point in agricultur...
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Chromosome-Level Genome Assembly of Fall Armyworm Sheds Light on Its Invasion and Pesticide Resistance
Fall armyworm (Spodoptera frugiperda) is a highly destructive pest that has rapidly spread across multiple continents...
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Microbial Diversity in Industrial Effluents: Unlocking Source Tracking Potential
Understanding the microbial diversity in industrial effluents is crucial for efficient environmental surveillance and...
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Unveiling the Genetic Diversity of Moso Bamboo: A Population Genomics Study
Bamboo has been an integral part of Chinese culture and daily life for centuries, serving not only as an essential na...
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Comparative Analysis of Clonal Evolution in Right- and Left-Sided Colon and Rectal Cancer
Tumor evolution is a dynamic and complex process, with variations in growth patterns significantly influencing diseas...
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Deciphering the Evolution of Neo-Y Chromosomes: Insights from the Spotted Knifejaw Genome
Sex chromosome evolution is one of the most fascinating processes in genomic research, with profound implications for...
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Global Lettuce Genomics: Unraveling the Domestication History and Genetic Diversity of Cultivated Lettuce
Lettuce (Lactuca sativa) is one of the most widely consumed leafy vegetables in the world, yet its genetic diversity ...
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Genomic Insights into Mangrove Rhizosphere Fungi: Understanding Microbial Adaptations in Coastal Ecosystems
Mangrove forests are among the most biologically diverse and ecologically productive ecosystems, hosting a rich array...
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SLR-superscaffolder: A Novel Scaffolding Tool for Synthetic Long Reads
Genome assembly is a fundamental component of genomics research, enabling the reconstruction of complete genetic sequ...
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Metagenomic Analysis Reveals Microbial Community Structure and Nitrogen Acquisition Strategies in the Indian Ocean
Despite being the third-largest ocean in the world, the Indian Ocean remains one of the least studied regions in term...
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Accurate Haplotype-Resolved Assembly in Human Trios Using Long Fragment Read Sequencing
Understanding how genetic variations are inherited and structured within an individual’s genome is key to advancing p...
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Chromosome-Level Genome Assembly of White-Spotted Bamboo Shark: Insights into Evolution and Immunity
Cartilaginous fish, such as sharks, represent an early branch in vertebrate evolution, offering valuable insights int...
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African Arowana Genome Provides Insights into Ancient Teleost Evolution
The evolutionary history of teleosts is deeply intertwined with continental drift, shaping their genetic diversity an...
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Deciphering the Microbial Taxonomy and Functionality of Mangrove Ecosystems
Mangrove ecosystems are unique coastal environments that support diverse microbial communities, playing a crucial rol...
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Chromosome-Level Genome Assembly of Indo-Pacific Humpback Dolphin
The Indo-Pacific humpback dolphin (Sousa chinensis) is a coastal cetacean species facing increasing threats due to ha...
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Chromosome-Level Genome Assembly and GWAS for Panax Notoginseng
Panax notoginseng (P. notoginseng), a medicinal herb with significant economic and therapeutic value, has long been s...
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Comparative Chloroplast Genomics of Mangrove Species: Phylogenetic Insights and Evolutionary Analysis
Mangrove ecosystems serve as critical environmental buffers between land and sea, hosting unique plant species that h...
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Genome Sequencing of Mekong Tiger Perch: Insights into Phylogeny and Conservation
The Mekong tiger perch (Datnioides undecimradiatus) is a vulnerable freshwater fish native to the Mekong basin in Ind...
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Lineage-Specific Evolution of Mangrove Plastid Genomes
Mangrove forests thrive in coastal tropical and subtropical regions, bridging the gap between terrestrial and marine ...
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Genomes of Early-Diverging Streptophyte Algae Shed Light on Plant Terrestrialization
The transition of plants from aquatic to terrestrial environments represents a pivotal moment in evolutionary history...
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Chromosome-Based Rubber Tree Genome Provides Insights into Evolution and Rubber Biosynthesis
The rubber tree (Hevea brasiliensis) is the primary source of natural rubber, a crucial industrial material with no s...
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Draft Genomes of Jackfruit and Breadfruit Provide Insights into Starch and Sugar Metabolism
Jackfruit (Artocarpus heterophyllus) and breadfruit (Artocarpus altilis) are two economically and nutritionally signi...
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Chromosome-Level Genome Assembly of Mangrove Fungus Penicillium variabile HXQ-H-1
Mangrove ecosystems host a diverse range of microorganisms, including fungi that play a crucial role in organic matte...
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Draft Genome Sequence of Solanum Aethiopicum: Advancing Disease Resistance and Drought Tolerance Research
The African eggplant (Solanum aethiopicum) is a vital crop cultivated across tropical Africa for its nutritional and ...
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Resequencing 545 Ginkgo Genomes: Unveiling the Evolutionary History of a Living Fossil
As one of the most ancient living plants, Ginkgo biloba has survived for over 200 million years, maintaining its resi...
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Exploring the Commensal Microbiome of the Sperm Whale
The commensal microbiota of marine mammals plays a crucial role in their health and adaptation to the oceanic environ...
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Resequencing 429 Chickpea Accessions: Insights into Genome Diversity and Domestication
Chickpea (Cicer arietinum) is a staple legume crop with immense nutritional and agricultural importance. Understandin...
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Chromosome-Level Genome Assembly of Sperm Whale: Insights into Marine Mammal Evolution
Marine mammals offer unique evolutionary models, demonstrating adaptations to aquatic environments through physiologi...
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Chromosome-Level Genome Assembly of Black Rockfish Provides Insights into the Evolution of Live Birth
The black rockfish (Sebastes schlegelii) is a teleost species that exhibits viviparity, a reproductive strategy in wh...
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Molecular Digitization of a Botanical Garden: High-Depth Genome Sequencing of 689 Vascular Plant Species
Genome sequencing has transformed plant research, offering insights into species diversity, evolution, and adaptation...
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Chromosome-Level Comparative Analysis of Brassica Genomes
Brassica species are essential for agriculture and evolutionary studies, with genomes shaped by polyploidization even...
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Draft Genomes of Five African Orphan Crops: Expanding Genetic Resources for Food Security
To diversify global food supplies and enhance nutrition security, underutilized crops—often referred to as orphan cro...
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Chromosome-Level Genome Assembly of Spotted Sea Bass
The spotted sea bass (Lateolabrax maculatus) is a commercially valuable fish widely cultivated in China. Despite its ...
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Chromosome-Level Reference Genome of the Siamese Fighting Fish
The Siamese fighting fish (Betta splendens) is well known for its highly aggressive behavior, making it a valuable mo...
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Population Genomics of Japanese Quail: Insights into Genetic Diversity and Domestication
The Japanese quail (Coturnix japonica) is a poultry species with significant agricultural and scientific value. As a ...
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Pearl Millet Genome Sequencing: A Resource for Improving Agronomic Traits in Arid Regions
Pearl millet (Cenchrus americanus) is a staple crop for over 90 million farmers in arid and semi-arid regions, partic...
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Genome Sequencing of the Pearl Oyster *Pinctada fucata martensii*: Insights into Biomineralization
Pearl-producing mollusks have long been recognized as economically valuable species, not only for their exquisite pea...
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Draft Genome Sequence of the Tibetan Medicinal Herb Rhodiola Crenulata
Rhodiola crenulata (R. crenulata) is a highly valued medicinal plant, particularly in traditional Chinese and Tibetan...
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Genomic Basis of Alternative Reproductive Strategies in the Ruff
The ruff (Philomachus pugnax) is a migratory wading bird with one of the most complex and fascinating mating systems ...
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Nature Biotechnology: Decoding the Upland Cotton Genome and Its Polyploid Evolution
Our 2015 study in Nature Biotechnology presents the first high-quality assembly of the cultivated Upland cotton (TM-1...
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Genome Draft of the Legless Anguid Lizard *Ophisaurus gracilis*
The transition from lizard-like to snake-like body forms represents one of the most intriguing evolutionary transform...
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Genome Sequencing of Phalaenopsis equestris: Unraveling Orchid Evolution and Floral Diversity
Orchids are one of the most diverse and fascinating plant families, displaying remarkable floral adaptations and ecol...
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Comparative Population Genomics Reveals the Domestication History of Peach
Peach (Prunus persica) is one of the most economically and culturally significant fruit crops, with a long history of...
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Genomic Variation Map of Cucumber: Insights into Domestication and Diversity
Most fruits consumed today are the result of long-term domestication and breeding efforts. However, the genetic basis...
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Genomic Landscapes of Chinese Hamster Ovary Cell Lines and Cricetulus griseus
Chinese hamster ovary (CHO) cells are the preferred production hosts for biopharmaceuticals, widely used for the deve...
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The Plant Cell: Tarenaya hassleriana Genome Sheds Light on Crucifer Evolution
Our collaborative study in The Plant Cell reveals how whole-genome duplication and subsequent gene evolution shaped t...
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Nature Biotechnology: First Domestic Goat Genome Assembly Using Optical Mapping
Our collaborative research in Nature Biotechnology presents the first high-quality reference genome of the domestic g...
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Foxtail Millet Genome Sequencing: Insights into Grass Evolution and Biofuel Potential
Foxtail millet (Setaria italica) is a drought-tolerant crop with rich nutritional value and historical significance, ...
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Nature Genetics: Maize HapMap2 Unlocks the Extensive Variation in a Genome in Flux
Our 2012 study in Nature Genetics characterized 55 million SNPs across 103 maize varieties, providing a transformativ...
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Nature: The Tomato Genome Sequence Decodes the Evolution of Fleshy Fruits
Our 2011 study in Nature, as part of the Tomato Genome Consortium, provides a high-quality reference genome of tomato...
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Resequencing 50 Accessions of Cultivated and Wild Rice for Agronomic Gene Identification
Rice (Oryza sativa) is a staple food crop that has undergone extensive domestication, resulting in significant phenot...
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Nature Biotechnology: Decoding the Genomic Blueprint of the Biopharmaceutical Workhorse - CHO Cells
Our 2011 study in Nature Biotechnology presented the first draft genome of the CHO-K1 cell line, providing a transfor...
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Resequencing 31 Wild and Cultivated Soybean Genomes: Insights into Genetic Diversity and Domestication
Soybean (Glycine max) is a critical crop globally, serving as a major source of protein and oil. Understanding its ge...
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